Pre-existing virus-specific CD8+ T-cells provide protection against pneumovirus-induced disease in mice
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چکیده
منابع مشابه
Pre-existing virus-specific CD8+ T-cells provide protection against pneumovirus-induced disease in mice
Pneumoviruses such as pneumonia virus of mice (PVM), bovine respiratory syncytial virus (bRSV) or human (h)RSV are closely related pneumoviruses that cause severe respiratory disease in their respective hosts. It is well-known that T-cell responses are essential in pneumovirus clearance, but pneumovirus-specific T-cell responses also are important mediators of severe immunopathology. In this st...
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متن کاملCorrection: CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
[This corrects the article DOI: 10.1371/journal.pntd.0005763.].
متن کاملCD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi causes illness in one million people each year, and 1 billion people are at risk. Without appropriate diagnosis and treatment, the disease can cause severe multiorgan failure with a case fatality rate of 7-15%. The cur...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2012
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2012.08.027